Easy Garlic-Infused Parmesan Chicken Pasta Casserole Recipe

If you’re craving a dish that brings together tender chicken, creamy textures, and bold garlic flavor, then you’re going to adore this Garlic-Infused Parmesan Chicken Pasta Casserole. It’s a perfect weeknight dinner that feels comforting but comes together with surprising ease. This casserole blends savory garlic, rich Parmesan cheese, and perfectly cooked pasta into a warm, creamy bake that’s guaranteed to satisfy the whole family. Whether you want something hearty after a long day or a dish that impresses without stress, this recipe fits the bill beautifully.

Why You’ll Love This Recipe

• Effortlessly delicious: This recipe is a one-pan wonder that minimizes cleanup while maximizing flavor.
• Comfort food perfected: Creamy, cheesy, and garlicky with tender chicken and pasta for a cozy meal everyone loves.
• Customizable to your taste: Easily swap ingredients or add veggies to tailor it to your preferences.
• Quick weeknight saver: Prep and bake in under an hour, so you can enjoy a homemade dinner fast.
• Great for leftovers: Reheats wonderfully, making it perfect for meal prep or next-day treats.

Ingredients You’ll Need

With just a handful of essential ingredients, this Garlic-Infused Parmesan Chicken Pasta Casserole balances creamy richness, sharp cheese, and vibrant garlic flavors. Each ingredient plays a role—whether it’s building the sauce or adding texture.

• Boneless, skinless chicken breast: Tender, lean protein that cooks quickly and soaks up the creamy sauce.
• Rotini or penne pasta: A sturdy pasta that holds sauce beautifully and provides a satisfying bite.
• Fresh garlic cloves: The star of the dish, delivering that irresistible garlic-infused aroma and taste.
• Parmesan cheese: Adds a sharp, nutty flavor that enriches the creamy base perfectly.
• Heavy cream or half-and-half: Creates the luscious sauce that brings the casserole together.
• Olive oil or butter: For sautéing garlic and chicken to enhance flavor and texture.
• Italian seasoning: A blend of herbs that adds a subtle aromatic lift.
• Salt and pepper: Simple seasoning that balances and enhances every bite.
• Mozzarella cheese (optional): Melts on top for extra gooey, golden cheesiness if you like.

Variations for Garlic-Infused Parmesan Chicken Pasta Casserole

The beauty of this casserole is how adaptable it can be. Whether you want to add more veggies, make it spicier, or adjust it to a dietary preference, it’s easy to swap or add ingredients that suit your cravings.

• Veggie boost: Add broccoli florets, spinach, or bell peppers for extra color and nutrients.
• Spicy kick: Mix in crushed red pepper flakes or a dash of cayenne for heat.
• Gluten-free swap: Use gluten-free pasta varieties to keep it friendly for gluten sensitivity.
• Low-carb alternative: Substitute pasta with zucchini noodles or cauliflower rice.
• Herb variations: Use fresh basil, thyme, or rosemary for a different herbal note.

How to Make Garlic-Infused Parmesan Chicken Pasta Casserole

Step 1: Prepare the pasta

Cook your chosen pasta according to the package instructions until al dente, then drain and set aside to prevent it from overcooking in the casserole.

Step 2: Sauté the chicken and garlic

In a large skillet, heat olive oil or butter, then add minced garlic to release its aroma. Add bite-sized chicken pieces, seasoning with salt, pepper, and Italian seasoning, cooking until just golden and cooked through.

Step 3: Make the creamy Parmesan sauce

In the same skillet, pour in heavy cream or half-and-half, stirring constantly as you bring it to a gentle simmer. Gradually whisk in grated Parmesan cheese until melted and creamy, creating a luscious sauce base.

Step 4: Combine pasta, chicken, and sauce

Mix the cooked pasta with the chicken and cream sauce in the skillet, ensuring every piece is coated in the garlic-Parmesan goodness.

Step 5: Bake the casserole

Transfer the mixture into a baking dish, top with mozzarella cheese if desired, and bake at 375°F (190°C) for 15-20 minutes until bubbly and golden on top.

Pro Tips for Making Garlic-Infused Parmesan Chicken Pasta Casserole

• Use freshly grated Parmesan: Avoid pre-grated cheese for a richer, creamier sauce without additives.
• Don’t overcook the pasta: Slightly undercook it to ensure the bake finishes it perfectly without turning mushy.
• Infuse garlic early: Sauté garlic gently in oil or butter to mellow the flavor and prevent bitterness.
• Season progressively: Taste and adjust salt and pepper at each stage for a balanced final dish.
• Let it rest: Allow the casserole to cool slightly before serving to let flavors meld wonderfully.

How to Serve Garlic-Infused Parmesan Chicken Pasta Casserole

Garnishes

Fresh parsley or basil sprinkled on top adds a pop of color and freshness that cuts through the creamy richness beautifully.

Side Dishes

Serve alongside a crisp green salad, garlic bread, or roasted vegetables to round out the meal with texture and variety.

Creative Ways to Present

Serve individual portions in mini ramekins for a charming presentation, or layer with extra herbs and shaved Parmesan for an elevated look.

Make Ahead and Storage

Storing Leftovers

Store any leftovers in an airtight container in the refrigerator for up to 3 days, making sure it cools before sealing to maintain freshness.

Freezing

This casserole freezes beautifully; place in a freezer-safe container for up to 2 months and thaw overnight in the refrigerator before reheating.

Reheating

Reheat leftovers in the oven or microwave until warmed through, adding a splash of cream or milk if the casserole has thickened too much.

FAQs

Can I use chicken thighs instead of breast?

Absolutely! Chicken thighs add more moisture and a richer flavor, making the casserole even more succulent.

Is this recipe freezer-friendly?

Yes, you can freeze the casserole either before or after baking, just be sure to thaw it completely before reheating.

Can I make this recipe dairy-free?

Yes, substitute the heavy cream with coconut milk or a dairy-free creamer and use a dairy-free Parmesan alternative.

How can I make this dish spicier?

Add red pepper flakes during the garlic sauté or mix in a bit of hot sauce to the creamy sauce before baking.

What type of pasta works best?

Short, sturdy pastas like rotini, penne, or rigatoni work best as they hold the sauce and bake well without becoming mushy.

Final Thoughts

This Garlic-Infused Parmesan Chicken Pasta Casserole is a fantastic recipe to keep in your back pocket for busy nights or cozy dinners. It’s simple, flavorful, and endlessly customizable, making it a guaranteed crowd-pleaser every time. Grab your ingredients, follow these steps, and get ready to enjoy a creamy, comforting meal that feels like a warm hug from the inside out.

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